| Bioactivity | ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1]. |
| Target | LCN2. |
| Invitro | ZINC00784494 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells[1].ZINC00784494 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells[1]. Cell Viability Assay[1] Cell Line: |
| Name | ZINC00784494 |
| CAS | 317328-17-9 |
| Formula | C20H14N2O3S |
| Molar Mass | 362.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22(16):8581. |
ZINC00784494
CAS: 317328-17-9 F: C20H14N2O3S W: 362.40
ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and re
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