| Bioactivity | ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect[1][2]. |
| In Vivo | ZD-9379 (5 mg/kg) reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion[1]. Animal Model: |
| Name | ZD-9379 |
| CAS | 170142-20-8 |
| Formula | C19H14ClN3O4 |
| Molar Mass | 383.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tatlisumak T, et al. A glycine site antagonist, ZD9379, reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion. Stroke. 1998;29(1):190-195. [2]. ZD 9379. Drugs R D. 1999;1(1):44-45. |
ZD-9379
CAS: 170142-20-8 F: C19H14ClN3O4 W: 383.79
ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-937
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