| Bioactivity | Z4P is a BBB-permeable IRE1 inhibitor (IC50: 1.11 μM). Z4P inhibits Glioblastoma cell growth. Z4P prevents glioblastoma relapse when administered together with Temozolomide (HY-17364)[1]. |
| Target | IC50: 1.11 μM (IRE1) |
| Name | Z4P |
| CAS | 2361760-87-2 |
| Formula | C19H24N2O2 |
| Molar Mass | 312.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pelizzari-Raymundo D, et al. A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment. iScience. 2023 Apr 24;26(5):106687. |