| Bioactivity | Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide. Z32439948 also exhibited neuroprotective effects against glutamate in SH-SY5Y cells[1]. |
| Invitro | Z32439948 (1-5 μM; 48 h) 对谷氨酸 (31 mM) 诱导的 SH-SY5Y 细胞死亡具有神经保护作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Z32439948 相关抗体: Cell Viability Assay[1] Cell Line: |
| CAS | 920845-86-9 |
| Formula | C25H26N4O4S |
| Molar Mass | 478.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lu X, et al. Discovery, Structure-Based Modification, In Vitro, In Vivo, and In Silico Exploration of m-Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS Chem Neurosci. 2024 Mar 20;15(6):1135-1156. |
Z32439948
CAS: 920845-86-9 F: C25H26N4O4S W: 478.56
Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide
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This product is for research use only, not for human use. We do not sell to patients.