| Bioactivity | Z21090 (ZL40) is a potent inhibitor of PDE4 with the IC50 value of 37.4 nM and oral bioavailability. Z21090 plays an important role in alcohol-related diseases research[1]. |
| Name | Z21090 |
| CAS | 2992690-71-6 |
| Formula | C12H14ClN3O3 |
| Molar Mass | 283.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lei Zheng, et al. Discovery of 4-Ethoxy-6-chloro-5-azaindazoles as Novel PDE4 Inhibitors for the Treatment of Alcohol Use Disorder and Alcoholic Liver Diseases. J Med Chem. 2023 Dec 29. |
Z21090
CAS: 2992690-71-6 F: C12H14ClN3O3 W: 283.71
Z21090 (ZL40) is a potent inhibitor of PDE4 with the IC50 value of 37.4 nM and oral bioavailability. Z21090 plays an imp
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