| Bioactivity | Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1]. |
| Name | Z-VDVAD-AFC |
| CAS | 219138-08-6 |
| Sequence | {Z}-Val-Asp-Val-Ala-Asp-{AFC} |
| Shortening | {Z}-VDVAD-{AFC} |
| Formula | C39H45F3N6O13 |
| Molar Mass | 862.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79. |
Z-VDVAD-AFC
CAS: 219138-08-6 F: C39H45F3N6O13 W: 862.80
Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3).
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