Bioactivity | Z-LEED-FMK is a caspase-13 and caspase-4 inhibitor. Z-LEED-FMK also inhibits caspase-1 processing in S. typhimurium-infected macrophages[1][2]. |
Name | Z-LEED-FMK |
CAS | 1135688-38-8 |
Formula | C32H45FN4O12 |
Molar Mass | 696.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Asch R J, et al. Role of Individual Amino Acids in the Action of Caspase Inhibitors as Proapoptotic Peptides for Human Leukemia. 2004. [2]. Imamura R, et al. Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol. 2010 May 15;184(10):5874-84. |