Bioactivity | Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA[1]. |
Name | Z-IETD-pNA |
CAS | 348079-18-5 |
Sequence | Z-Ile-Glu-Thr-Asp-pNA |
Shortening | Z-IETD-pNA |
Formula | C33H42N6O13 |
Molar Mass | 730.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yu-Hsuan Lan, et al. Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells. Oncol Rep. 2011 Feb;25(2):419-24. |