| Bioactivity | Z-GGF-CMK is a protease inhibitor, inhibits ClpP1P2 and proteasome. Z-GGF-CMK exhibits cytotoxic activity against HepG2 cells with a CC50 value of 125 μM[1]. |
| Name | Z-GGF-CMK |
| CAS | 35172-59-9 |
| Sequence | {Cbz}-Gly-Gly-Phe-{CMK} |
| Shortening | {Cbz}-GGF-{CMK} |
| Formula | C22H24ClN3O5 |
| Molar Mass | 445.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Moreira W, et, al. Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. Front Microbiol. 2017 Apr 27;8:746. |
Z-GGF-CMK
CAS: 35172-59-9 F: C22H24ClN3O5 W: 445.90
Z-GGF-CMK is a protease inhibitor, inhibits ClpP1P2 and proteasome. Z-GGF-CMK exhibits cytotoxic activity against HepG2
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