Bioactivity | Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1]. |
Target | Papain, Cathepsins B, Cathepsins L, Cathepsins V, Cathepsins S, Cathepsins X |
Name | Z-DEVD-CMK |
CAS | 250584-13-5 |
Sequence | {Cbz}-Tyr-Val-Ala-Asp-{CMK} |
Shortening | {Cbz}-YVAD-{CMK} |
Formula | C27H35ClN4O12 |
Molar Mass | 643.04 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10(8):881-8. |