Bioactivity | Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis by inhibiting the activity of caspase-12 and reducing the activity of caspase-9[1]. |
CAS | 1416658-51-9 |
Sequence | {Z}-Ala-Thr-Ala-Asp-{FMK} |
Shortening | {Z}-ATAD-{FMK} |
Formula | C23H31FN4O9 |
Molar Mass | 526.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhao CQ, et al. Both endoplasmic reticulum and mitochondria are involved in disc cell apoptosis and intervertebral disc degeneration in rats. Age (Dordr). 2010 Jun;32(2):161-77. |