Bioactivity | Z-APF-CMK is a specific inhibitor of Ca2+-regulated nuclear scaffold protease (CRNSP)[1]. |
Name | Z-APF-CMK |
CAS | 217658-18-9 |
Sequence | Z-Ala-Pro-Phe-{Chloromethylketone} |
Shortening | Z-APF-{Chloromethylketone} |
Formula | C26H30ClN3O5 |
Molar Mass | 499.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang D, et al. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5746-51. |