| Bioactivity | Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor[1]. |
| Invitro | Yp537 (5-50 μM; 1 h) abolishes the formation of the hER-ERE complex. And dose not inhibit the formation of the STAT1-serum-induced element complex[1].Yp537 binds to a SH2-like domain, and interferes with the SH2-like phosphopeptide coupling mechanism between hER monomers[1]. |
| Name | Yp537 |
| CAS | 166664-90-0 |
| Shortening | CNVVPL-Tyr(PO3H2)-DLLLE |
| Formula | C64H104N13O22PS |
| Molar Mass | 1470.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |