Bioactivity | Yohimbine Hydrochloride Standard is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis. |
In Vivo | Yohimbine Hydrochloride Standard (0.2 mg/kg; ip, 连续注射 14 天; 每次在压力训练前 1 小时注射) 显著降低了浸泡冷水的大鼠的性唤起和勃起。引起睾酮、黄体生成素 (LH) 和卵泡刺激素 (FSH) 水平的降低以及胆固醇含量的降低,同时导致交配活动的减少。Yohimbine Hydrochloride Standard 可纠正应激的雄性大鼠交配行为[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 65-19-0 |
Formula | C21H27ClN2O3 |
Molar Mass | 390.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Docherty JR, et al. Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat. Eur J Pharmacol. 2012 Mar 15;679(1-3):90-4. |