| Bioactivity | Yatein is a lignan isolated from A. chilensis, with antiproliferative activity[1]. Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression[2]. |
| Invitro | Yatein induces cell-cycle arrest at G2/M phase (5 μM; 24 hours) and enhances G2/M phase-related protein expression (5 μM; 6-12 hours) in human lung adenocarcinoma A549 and CL1-5 cells[3].Yatein (5 μM; 6-12 hours) induces DNA damage through activation of the ATM/ATR pathway in human A549 and CL1-5 cells[3].Yatein (5 μM; 6 hours) affects microtubule dynamics by inhibiting tubulin polymerization[3]. Cell Cycle Analysis[3] Cell Line: |
| Name | Yatein |
| CAS | 40456-50-6 |
| Formula | C22H24O7 |
| Molar Mass | 400.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |