| Bioactivity | YZ51 is a derivative of Osalmid (HY-B2116) with stronger ribonucleotide reductase (RR) inhibitory activity and HBV replication inhibition ability than Osalmid. The IC50 of YZ51 against recombinant RR activity is 0.6 μM, and the IC50 against HepG2.2.15 cell RR activity is 23.7 μM[1]. |
| CAS | 1835652-66-8 |
| Formula | C16H14FNO2 |
| Molar Mass | 271.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xia Liu, et al. "Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein." Biochemical Pharmacology 103 (2016): 118-128. |