| Bioactivity | YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC50 value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and drug resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria[1]. |
| Target | IC50: 3.686 μM (Pseudomonas aeruginosa) |
| Name | YXL-13 |
| CAS | 2415981-79-0 |
| Formula | C13H15BrN2O4 |
| Molar Mass | 343.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiang K, Yan X, Yu J, et al. Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1. Eur J Med Chem. 2020;194:112252. |