| Bioactivity | YQA14 is a high affinity dopamine D3 receptor antagonist. YQA14 is anti-opioid addiction agent. YQA14 inhibits Morphine/Cocaine-induced conditioned place preference (CPP) in animals[1][2]. |
| Target | D3 receptor |
| Name | YQA14 |
| CAS | 1221408-42-9 |
| Formula | C23H27ClN4O3 |
| Molar Mass | 442.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hu R, et al. The dopamine D3 receptor antagonist YQA14 that inhibits the expression and drug-primed reactivation of morphine-induced conditioned place preference in rats. Eur J Pharmacol. 2013 Oct 24:S0014-2999(13)00782-6. [2]. Song R, et al. Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice. Neuropharmacology. 2013 Sep;72:82-7. |