PeptideDB

YO-PRO-1

CAS: 152068-09-2 F: C24H29I2N3O W: 629.32

YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells. YO-PRO-1 is commonly used for the detection of apoptosis and necrosis. YO-PRO-1 has a high affinity for DNA and is essentially non-fluorescent when not bound to DNA. When apoptosis occurs, the permeability of the cell membrane changes. YO-PRO-1 can enter apoptotic cells and bind to DNA and emit bright green fluorescence. Therefore, YO-PRO-1 is often used together with propidium iodide (PI) to analyze and identify apoptotic and necrotic cells.
Name YO-PRO-1
CAS 152068-09-2
Formula C24H29I2N3O
Molar Mass 629.32
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.