PeptideDB

YM-I-26

CAS: 2585015-90-1 F: C28H33ClN2O5S2 W: 577.16

YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse mi
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Bioactivity YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse microglial BV2 cells and inhibits the production of IL-1β and IL-10. YM-I-26 can be used to study the immunomodulatory activity associated with inflammation[1].
CAS 2585015-90-1
Formula C28H33ClN2O5S2
Molar Mass 577.16
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Biby S, et al. Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome[J]. ACS Chemical Neuroscience, 2024.