| Bioactivity | YM-17690 is a LTD4 and LTE4 agonist, with a pKi value of 9.28 for [3H]LTD4. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16, 3.9, and 22 nM, respectively. YM-17690 can be used in research related to asthma and inflammation[1]. |
| CAS | 108806-41-3 |
| Formula | C28H29NO7 |
| Molar Mass | 491.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tomioka K, et al. Isolated tissue and binding studies of YM-17690, a novel and non-analogous leukotriene agonist. J Pharm Pharmacol. 1987 Oct;39(10):819-24. |