| Bioactivity | YL-5092 is an inhibitor for YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). YL-5092 inhibits acute myeloid leukemia cell with IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor efficacy in MOLM-13 or U937 xenograft mice[1]. |
| Formula | C22H14F3N3O2S |
| Molar Mass | 441.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang S, et al. Discovery of a selective YTHDC1 inhibitor that targets acute myeloid leukemia[J]. 2023. |