| Bioactivity | YEATS4-IN-1 (Compound 4d) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 33 nM[1]. |
| In Vivo | The pharmacokinetic parameters of NAMPT degrader-3(4d)(p.o., 100 mg/kg) in mice 4d |
| Name | YEATS4-IN-1 |
| Formula | C24H36N4O2 |
| Molar Mass | 412.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Allyn T Londregan, et al. Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4. J Med Chem. 2023 Jan 12;66(1):460-472. |