| Bioactivity | YDR1 is a potent PROTAC SMARCA2 degrader, with the DC50 of 7.7 nM(Sturcture Note:(Blue: Cereblon ligand (HY-W087383), Black: linker；Pink: SMARCA2 ligand (HY-44012B))[1]. |
| CAS | 2951015-31-7 |
| Formula | C44H49FN10O5 |
| Molar Mass | 816.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sasikumar Kotagiri, et al. Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors. bioRxiv [Preprint]. 2024 Aug 26:2024.08.23.608456. |