| Bioactivity | YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD)[1]. |
| Sequence | Tyr-Ala-Arg-Ala-Ala-Ala-Arg-Gln-Ala-Arg-Ala-Lys-Ala-Leu-Asn-Arg-Gln-Gly-Leu-Val-Ala-Ala |
| Shortening | YARAAARQARAKALNRQGLVAA |
| Formula | C99H172N38O27 |
| Molar Mass | 2326.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dartora VFC, et al. Chitosan hydrogels with MK2 inhibitor peptide-loaded nanoparticles to treat atopic dermatitis. J Control Release. 2023 Oct;362:591-605. |