Xanthine oxidoreductase-IN-3

CAS: 651769-78-7 F: C14H10ClN5O W: 299.72

Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanth

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Bioactivity	Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia[1].
Target	IC50: 26.3 nM (xanthine oxidoreductase)
In Vivo	Xanthine oxidoreductase-IN-3 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 3 h 显示出降低急性高尿酸血症小鼠尿酸的作用[1]。 Animal Model:
Name	Xanthine oxidoreductase-IN-3
CAS	651769-78-7
Formula	C14H10ClN5O
Molar Mass	299.72
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.