| Bioactivity | Xanthine oxidase-IN-16 is potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 102 nM. Xanthine oxidase-IN-16 shows significant efficacy in hyperuricemia rats[1]. |
| In Vivo | Xanthine oxidase-IN-16（化合物 12h；10-40 mg/kg；口服；一次）对Potassium oxonate (HY-17511) 诱发的高尿酸血症大鼠有显著的降尿酸作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| Formula | C17H15NO4 |
| Molar Mass | 297.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Haiqi Xu, et al. Design, synthesis, and evaluation of chalcone derivatives as xanthine oxidase inhibitors. European Journal of Medicinal Chemistry. Volume 279, 5 December 2024, 116893. |
Xanthine oxidase-IN-16
CAS: F: C17H15NO4 W: 297.31
Xanthine oxidase-IN-16 is potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 102 nM. Xanthine oxid
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