| Bioactivity | Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model[1]. |
| Target | IC50: 1.8 nM (Adenosine A1 receptor)IC50: 114 nM (Adenosine A2 receptor) |
| In Vivo | Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg[1]. Animal Model: |
| Name | Xanthine amine congener dihydrochloride |
| CAS | 1962928-23-9 |
| Formula | C21H30Cl2N6O4 |
| Molar Mass | 501.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. P F Morgan, et al.Potent Convulsant Actions of the Adenosine Receptor Antagonist, Xanthine Amine Congener (XAC). Life Sci. 1989;45(8):719-28 |
Xanthine amine congener dihydrochloride
CAS: 1962928-23-9 F: C21H30Cl2N6O4 W: 501.41
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagon
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