| Bioactivity | XQ2B is a cGAS inhibitor targeting protein-DNA interactions and phase separation. XQ2B inhibits herpes simplex virus 1 (HSV-1)-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo[1]. |
| Name | XQ2B |
| Sequence | Cyclo({d-Phe}-Ala-Thr-Arg-Leu-{d-phe}-Pro-Val-Arg-Leu) |
| Shortening | Cyclo({d-Phe}-ATRL-{d-phe}-PVRL) |
| Formula | C59H92N16O11 |
| Molar Mass | 1201.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang X, et al. Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation. Nat Commun. 2023 Oct 2;14(1):6132. |