| Bioactivity | XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases[1]. |
| Invitro | XMD-17-51 是一种嘧啶并二氮卓酮化合物，能够调节蛋白激酶，包括 MPS1 (TTK)、ERK5（BMK1、MAPK7）、polo 激酶 1、2、3 或 4、Ack1、Ack2、Abl、DCAMKL1 , ABL1, Abl 突变体, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR- Met、Tie2、MET、FGFR3、Aurora、Axl、Bmx、BTK、c-kit、CHK2、Flt3、MST2、p70S6K、PDGFR、PKB、PKC、Raf、ROCK-H、Rsk1、SGK、TrkA、TrkB 和 TrkC， 并可用于治疗各种疾病、病症或病症[1]。 |
| Name | XMD-17-51 |
| CAS | 1628614-50-5 |
| Formula | C21H24N8O |
| Molar Mass | 404.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. WO 2014145909 A2. |