Bioactivity | XD2-149 is a PROTAC targeting STAT3. XD2-149 consists of PROTAC target protein ligand Napabucasin (HY-13919), E3 ligase Thalidomide (HY-14658), and Linker NH2-C5-Azacyclohexane-N-Boc (HY-159572). The conjugate of E3 ligase + linker is Thalidomide-NH-C5-azacyclohexane-N-Boc (HY-159571), and the active control of the target protein ligand is Thalidomide acid (HY-159573)[1]. |
Target | STAT3 |
CAS | 2710221-08-0 |
Formula | C38H39N5O8 |
Molar Mass | 693.74 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |