| Bioactivity | XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XAV-939 is a tankyrase inhibitor[1]. |
| Invitro | XAV-939 (GMP) (5 μM; 2 μM for 3 days; 1 μM) induces human pluripotent stem cells (hPSCs) to post-mitotic cortical neurons differentiation[1].XAV939 (GMP) promotes anterior CNS identity[1]. RT-PCR[1] Cell Line: |
| Name | XAV-939 (GMP) |
| CAS | 284028-89-3 |
| Formula | C14H11F3N2OS |
| Molar Mass | 312.31 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Yuchen Qi, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35(2):154-163. |
XAV-939 (GMP)
CAS: 284028-89-3 F: C14H11F3N2OS W: 312.31
XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxi
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