| Bioactivity | Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg. |
| CAS | 93413-90-2 |
| Formula | C16H26ClNO2 |
| Molar Mass | 299.84 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Wy-45494 (hydrochloride) (Standard)
CAS: 93413-90-2 F: C16H26ClNO2 W: 299.84
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride). This product is intended for
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This product is for research use only, not for human use. We do not sell to patients.