PeptideDB

Wnt/β-catenin agonist 3

CAS: 912790-59-1 F: C16H15ClN4O2 W: 330.77

Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be u
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Bioactivity Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis[1].
Invitro Wnt/β-catenin agonist 3 (compound 98; 24 h; HEK293 和 SW480 细胞) 在 120 μM 浓度下,显示出 54% 的细胞活性[1]。Wnt/β-catenin agonist 3 (30 μM 和 60 μM; 24 h; HEK293 细胞) 是 β-Catenin 的激活剂,并沉积 β-Catenin[1]。Wnt/β-catenin agonist 3 (11 μM; 4 d) 诱导 ST2 细胞系分化为成骨细胞和钙沉积[1]。 Western Blot Analysis[1] Cell Line:
Name Wnt/β-catenin agonist 3
CAS 912790-59-1
Formula C16H15ClN4O2
Molar Mass 330.77
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. Cho JW, et al. Isoxazole derivatives and use thereof. WO2007078113A1.