Bioactivity | Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1]. |
Target | IC50: 45 nM (wnt) |
Invitro | Wnt pathway inhibitor 3 (compound 41) (0-100 000nM; 72 h) 显示抗增殖活性,对 HS68、Dld1、HCT116、SW480 细胞的 IC50 值分别为 641、470、551、618 nM[1]。 |
Name | Wnt pathway inhibitor 3 |
CAS | 663213-98-7 |
Formula | C21H17BrN2O5 |
Molar Mass | 457.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Michael Boutros, et al. Chromene derivatives and their analoga as wnt pathway antagonists. US20130296344A1. |