Bioactivity | Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist[1][2]. |
Invitro | Wistin, is a PPARγ agonist that can induce the mRNA expression of the PPARγ target gene adiponectin in mouse 3T3-L1 cells[2].Wistin inhibits cellular triglyceride accumulation in hepatocytes (PCPT1a, ACO, and ACS, respectively[2].Treatment with Wistin for 48 h significantly decreases the amount of cellular TG in mouse primary hepatocytes in a dose-dependent manner[2].Treatment with wistin enhanced the marker of adipocyte differentiation, such as triglyceride accumulation in 3T3-L1 cells[3]. RT-PCR[2] Cell Line: |
Name | Wistin |
CAS | 19046-26-5 |
Formula | C23H24O10 |
Molar Mass | 460.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |