| Bioactivity | Windorphen is a Wnt/β-catenin signal inhibitor that specifically targets the function of the c-terminal transactivation domain of β-catenin-1 but not β-catenin-2. Windorphen selectively targets p300, disrupting the association of the mammalian β-catenin with p300 but not CBP[1]. |
| Name | Windorphen |
| CAS | 19881-70-0 |
| Formula | C17H15ClO3 |
| Molar Mass | 302.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jijun Hao, et al. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Rep. 2013 Sep 12;4(5):898-904. |