| Bioactivity | WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM[1]. |
| Invitro | WJM-715 提高大鼠肝细胞 pH 7.4 时的水溶性至 60 μM 以及代谢稳定性至 68 μL/min/106cells[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> WJM-715 相关抗体: |
| In Vivo | WJM-715 (50 mg/kg，口服) 在 swiss outbred 小鼠体内的半衰期为 5.9 小时[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C19H22Cl2N4O4S |
| Molar Mass | 473.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nguyen W, et al., Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein. Eur J Med Chem. 2024 Mar 25;270:116354. |