| Bioactivity | WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders[1]. |
| CAS | 2839552-68-8 |
| Formula | C25H33F2N5O2 |
| Molar Mass | 473.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. BONAZZI S, et al., Pyrazolopyridine Derivatives and Uses thereof. US20240158374A1. |
WIZ degrader 1
CAS: 2839552-68-8 F: C25H33F2N5O2 W: 473.56
WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ de
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