Bioactivity | WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells[1]. |
Name | WH-15 |
CAS | 1264748-47-1 |
Formula | C31H43N2O18P3 |
Molar Mass | 824.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Huang W, et al. A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes. ACS Chem Biol. 2011 Mar 18;6(3):223-8. |