| Bioactivity | WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation[1]. | ||||||||||||
| Name | WEHI-345 analog | ||||||||||||
| CAS | 1354825-62-9 | ||||||||||||
| Formula | C23H25N7O | ||||||||||||
| Molar Mass | 415.49 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Nachbur U, et al. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015 Mar 17;6:6442. |
WEHI-345 analog
CAS: 1354825-62-9 F: C23H25N7O W: 415.49
WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.1
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