| Bioactivity | WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC50 value of ≦ 100 nM. WEE1-IN-6 inhibits cell proliferation[1]. |
| Target | DC50: ≦ 100 nM (WEE1) |
| Invitro | WEE1-IN-6 (compound 110) 在 H1048 细胞中显示出抗增殖活性，IC50 值为 ≤ 25 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> WEE1-IN-6 相关抗体: |
| CAS | 2928524-08-5 |
| Formula | C45H52FN11O4 |
| Molar Mass | 829.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fu Liqiang, et al. Wee1 protein kinase degradation agent and use thereof. WO2023083194A1. [2]. Hangzhou Glubio Pharmaceutical Co., Ltd. Fused 2-aminopyrimidine compounds as Wee1 protein kinase degradation inhibitors and their preparation, pharmaceutical compositions and use in the treatment of proliferative diseases. World Intellectual Property Organization, WO2023083194 A1 2023-05-19 |
WEE1-IN-6
CAS: 2928524-08-5 F: C45H52FN11O4 W: 829.96
WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC50 value of ≦ 100 nM. WEE1-IN-6 inhibits cell prol
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