| Bioactivity | WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively[1]. |
| CAS | 2975172-98-4 |
| Formula | C26H29FN8OS2 |
| Molar Mass | 552.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang Y, et al. Wee1 inhibitor optimization through deep-learning-driven decision making. Eur J Med Chem. 2024 Sep 29;280:116912. |
WEE1-IN-11
CAS: 2975172-98-4 F: C26H29FN8OS2 W: 552.69
WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3,
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