| Bioactivity | WAY 629 is a potent and selective 5-HT2C agonist with EC50s of 426, 260000 nM for 5-HT2C and 5-HT2A, respectively. WAY 629 decreases feeding behavior[1][2]. |
| In Vivo | WAY 629 (30 mg/kg; i.p.) 降低大鼠的进食行为[1]。WAY 629 (30 mg/kg; i.p.) 降低小鼠大脑中 NPY mRNA 的表达[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 57756-45-3 |
| Formula | C15H18N2 |
| Molar Mass | 226.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sabb AL, et al. Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor. Bioorg Med Chem Lett. 2004 May 17;14(10):2603-7. [2]. Aoki M, et al. Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. Eur J Neurosci. 2016 May;43(9):1219-28. |