WAY-267464_product_DataBase

Bioactivity	WAY-267464 is a non-peptide oxytocin receptor (OTR) agonist. WAY-267464 can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder[1].
In Vivo	WAY-267464 (i.p., 100 mg/kg) has antagonism of the memory-enhancing effects of AVP (0.005 mg/kg) on social recognition at a retention interval of 120 min[1].WAY-267464 (i.p., 10 and 30 mg/kg) has the antagonist effects on the arginine vasopressin Vasopressin (HY-P0049) (AVP)-induced (0.005 mg/kg) facilitation of social recognition at a retention interval of 120 min[1].WAY-267464 (i.p., 30 and 100 mg/kg, given alone) impairs memory at a 30 min retention interval[1]. Animal Model:
Name	WAY-267464
CAS	847375-16-0
Formula	C32H35N7O4
Molar Mass	581.66
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Callum Hicks, et al. WAY 267,464, a non-peptide oxytocin receptor agonist, impairs social recognition memory in rats through a vasopressin 1A receptor antagonist action. Psychopharmacology (Berl). 2015 Aug;232(15):2659-67.

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