| Bioactivity | WAY-181187 (SAX-187) oxalate is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM. WAY-181187 oxalate mediates 5-HT6 receptor-dependent signal pathways, such as cAMP, Fyn and ERK1/2 kinase, as specific agonist[1][2]. |
| Invitro | WAY-181187 (SAX-187) oxalate (1 and 10 μM) increases activation of ERK1/2. WAY181187 also increases Fyn kinase activity[2]. |
| Name | WAY-181187 oxalate |
| CAS | 1883548-85-3 |
| Formula | C17H15ClN4O6S2 |
| Molar Mass | 470.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
WAY-181187 oxalate
CAS: 1883548-85-3 F: C17H15ClN4O6S2 W: 470.91
WAY-181187 (SAX-187) oxalate is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.
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