PeptideDB

WAY-150138

CAS: 273388-09-3 F: C22H18Cl2FN3O3S W: 494.37

WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled[1][2]
CAS 273388-09-3
Formula C22H18Cl2FN3O3S
Molar Mass 494.37
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. William W. Newcomb, et al. Inhibition of Herpes Simplex Virus Replication by WAY-150138: Assembly of Capsids Depleted of the Portal and Terminase Proteins Involved in DNA Encapsidation. 2002 Oct; 76(19): 10084–10088. [2]. M van Zeijl, et al. Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: resistance maps to the UL6 gene. J Virol. 2000 Oct;74(19):9054-61.