Bioactivity | WAY-100289 is an orally active antagonist for 5-HT3 receptor, that exhibits high affinity to the isolated rat vagus nerves with pA2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats[1]. |
CAS | 136013-69-9 |
Formula | C20H27N3O3 |
Molar Mass | 357.45 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rhodes K F, et al. WAY 100289: Pharmacological profile of a novel 5‐HT3 receptor antagonist[J]. Drug development research, 1993, 28(2): 128-140. |