Bioactivity | Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018[1]. |
Target | B7-H3 |
Name | Vobramitamab |
CAS | 2490556-50-6 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brignole C, et al. Anti-tumor activity of vobramitamab duocarmazine (MGC018), an investigational duocarmycin-based anti-B7-H3 antibody-drug conjugate (ADC), in preclinical neuroblastoma models[J]. Cancer Research, 2023, 83(7_Supplement): 2981-2981. |