| Bioactivity | VinclozolinM2-2204 is a androgen receptor (AR) degrader, with an DC50 of 200 nM in LNCaP prostate cancer cells. VinclozolinM2-2204 induces the formation of AR+LC3+ autophagic membranes. VinclozolinM2-2204 can be used for the research of cancer[1]. |
| Formula | C43H51Cl2N3O9 |
| Molar Mass | 824.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904. doi: 10.1038/s41467-022-28520-4. Erratum in: Nat Commun. 2022 Apr 12;13(1):2108. |